产品货号:
Z31908
中文名称:
CD35/CR1抗体
英文名称:
Anti-CD35/CR1 Antibody (Clone#OTI2A8)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CD35/CR1 Antibody (Clone#OTI2A8) |
指标别名 | C3b/C4b receptor;C3BR;CD35;Complement receptor type 1;CR1;KN |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC |
基因名称 | CR1 |
克隆号 | OTI2A8 |
抗体来源 | Mouse |
抗体类型 | IgG2b |
免疫原 | Human recombinant protein fragment corresponding to amino acids 1900-2039 of human CR1 (NP_000564) produced in E.coli. |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1.The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes,leukocytes,glomerular podocytes,and splenic follicular dendritic cells.The Knops blood group system is a system of antigens located on this protein.The protein mediates cellular binding to particles and immune complexes that have activated complement.Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas,mesangiocapillary glomerulonephritis,systemic lupus erythematosus and sarcoidosis.Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting,conferring protection against severe malaria.Alternate allele-specific splice variants,encoding different isoforms,have been characterized.Additional allele specific isoforms,including a secreted form,have been described but have not been fully characterized.[provided by RefSeq,Jul 2008] |
Uniprot ID | P17927 |
基因名全称 | Complement receptor type 1 |
推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:500 |
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